Skin the concept
skin wrapped around the body, contact with the
external environment, to protect, feeling, regulating body temperature,
secretion and excretion. It protects the body organs and tissues from the
external environment in the mechanical, physical, the damage of harmful chemical
and biological factors, to prevent the loss of the organization a variety of
nutrients, electrolytes and water. skin contains many sensory nerve endings, can
sense cold, heat, pain, touch and pressure stimulation of the skin through the
sebum excretion of metabolites of the body with sweat. the thickness of the skin
with the parts, and general between in 0.5mm4mm, points the outer and inner
layers of the epidermis and dermis of epidermal epithelial cells of various
shape, size constitute these cells by primary outside goes on to differentiate
into spinous layer, the grain layer, the transparent layer and the stratum
corneum, this process is the diagonalization process, the transparent layer
exists only in charge of extension parts. dermis is divided into the depth of
two layers, the dermal fat and other organizations. < br> the scar
scar, namely what we call the scar is a general concept, it is collectively
referred to as the skin after various traumas caused by the appearance of normal
skin shape and histopathological changes. it is the surface of the body
naturally healing process of a normal, inevitable physiological responses, the
inevitable result of the wound healing process, scar tissue is a do not have
normal skin, loss of normal vitality, abnormal sound organization which not only
destroyed the surface America has also hampered the physiological function of
tissues and organs, or even disability.
scar causes
of Chinese medicine
scar formation is divided into external and internal factors external factors
are the external factors acting on the surface of the body,
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foreign body, wound infection after surgery, the surface tension is too large,
burns, burns damage the dermis and subcutaneous tissue to scar formation.
internal refers to the body's own qualities, race, individual quality, metabolic
status, age and nutritional status, other diseases pigment deposition conditions
and the formation of
scar the mechanism
studies have shown that
fibroblast cells, cytokines, extracellular matrix of the three scar formation
plays an important role in scar morphology of the stratum corneum thin, uneven
distribution of fibrous, some parallel to each other, some woven into nets, a
small gap of the structure loose; the epidermis and dermis occupies a rich
capillary, common at 40 magnification in a field of view 10mm13 capillary
cross-section of the root; prickle cell layer is more than 13 --- 15 irregular
prickle cells; into fiber cells, vascular endothelial cells TGFmm1 (transforming
growth factor), and collagen deposition in the scar tissue within the dermis see
various forms of fibroblasts and myofibroblasts in a large number of
disorganized, coarse collagen fibers and fibrous tissue with rhabdoid features;
scar into active fibroblasts and collagen secretion of strong mast cell number,
function, these changes with the scars gradually The maturing mitigation; that
scarring, contracture, and fibroblast cells, cytokines, myofibroblasts, vascular
endothelial cell proliferation and function is active, a large number of
collagen deposition and changes are closely related.
by various periods
dynamic changes in hypertrophic scars and found that VEGF (vascular endothelial
growth factor) with the development of hypertrophic scars, the expression level
to further increase the peak, the expression of in 4mm6 a hypertrophic scars. of
PDGF (platelet derived growth factor) and its receptor significantly enhanced
performance in the scar tissue
This study also showed that post-traumatic
skin fibroblasts, the rough endoplasmic reticulum proliferation and expansion
into the capsule, the cytoplasm microfilaments and microtubules increased in the
granulation tissue, and as early as the mid-proliferative scar muscle fibroblast
content increases, the actin filaments arranged along the shrinkage direction
equal systolic function closely near the collagen fibers, tight at this time
posted in the muscle fibroblast cell surface collagen fibers change curved or
spiral of, fibroblasts continue synthesis of collagen and matrix, the formation
of a rigid structure, contracture hardened scar tissue, leading to local
deformities and functional barriers around the contraction state of muscle
fibroblast cells scar tissue mast cell density increases, the ammonia of 5 -
hydroxytryptamine, histamine increased the blood vessels, blood supply,
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TN, inflammatory cell infiltration, tissue ischemia and hypoxia, decreased
collagenase activity, collagen degradation imbalance, damage the organization
itself healing; the 1 - 3 by the red point of light shaped into a bright red
flakes, surface rough, induration, itching obvious; scars continue to grow of 3
- 6 months, the color changed from red to purple, the surface revealed
capillaries, scars of a few millimeters thick, hard texture, inelastic, a year
or more scars mature, become light brown, the surface of blood vessels
disappear, itching symptoms, scars soften thin, but the dysfunction is not easy
to improve. < br> the scars diagnosis
etiology: scar, multiple trauma,
surgery, burns, burns, chemical injury, vaccination,
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dunks high, infection, acne, insect bites and other skin damage.
symptoms: scarring in the active proliferation of multi-local irritating
itching, pain, rainy days, and eating spicy food after the increase, accompanied
by severe local dysfunction
forms: strip, circular, oval, irregular, one or
more connected into the film, webbed, the bridge above the skin or sunken skin
color: a little red, pink, red, purple, crimson, or depigmentation.
texture:
soft, slightly hard, hard, hard, or from the the blisters
thickness : thin,
thin, slightly thick, thick, obvious thickening.
parts: one or more.
:
observe whether more than the original injury the range
temperature: a large
area of ??hypertrophic scars can be reduced skin cooling effect, affect the
ability to regulate temperature, there
elevated body temperature.
malformations: the scar to the body caused by dysfunction the situation
complications: with or without infection, ulcers, leakage Road and crypt
The physical scars: the performance of surface scars after wound healing is
increasing steadily, not only affect the appearance, and local pain, itching,
redness and swelling in the joints hinder movement
above conditions have to
be diagnosed scar.
, scar classification < br> from medical records
and histological classification: normal skin scars, hypertrophic scars, keloids
three
2 The clinical manifestations and organizations learn to change the
classification
A. superficial or flat scars
B. cords or contracture by
scar
C. webbed scar
D. pitting by scar
E. bridging and mastiff-like
scar
F. atrophic scars
G. Keloids and scarring the H. depigmentation
cancer
scar.
scars course and outcome of
scars from skin lesions
began to peak three months for the acute proliferative phase a 3mm6 months of
general 1mm2 natural maturation also 10 years is still hyperplasia up to 19
years is still in the proliferative phase. status quo
present treatment
of scar scar crowd is a huge group in the present, especially in recent years a
variety of accidental injuries a substantial increase, and the scars are mostly
in the exposed parts of the formation of scar surgery and cosmetic plastic
surgery is also growing, According to authoritative statistics, Asians accounted
for 85.68% of physical scars,
leather
belts, and China is high physical scars country, the physical scars crowd
accounted for more than 85%, scar crowd of more than 90%. the treatment of scars
at home and abroad using local drug closed, the surgical removal of skin
grafting, crystal wear scar surgery, balloon dilatation, immunotherapy (vascular
endothelial growth factor (VEGF) antibody injection therapy) gene therapy ,
radiation therapy, compression therapy, hormone therapy, silicone and other
therapies. in clinical practice is not very mature, efficacy remains to be seen,
some required a long time, pain, and many of them not working well. Chinese
medicine as early as 2,000 years discussed on the formation and treatment of
scars, the the Neijing camp gas not from the inverse in the flesh, is born
bloated pathogenic cold off the meridian into the blood weeping, blood weeping
barrier, different Wei gas owned by the, not only repeated, so carbuncle Wei, go
hand in hand up and down, that the wing guard, pass the meridian, Rong solid on
the outside. Ying Qi and by the gas barrier can not wing solid on the outside,
and finally made the race and quality, individual quality, metabolic status,
age, and nutritional status, other diseases pigmentation related. external
refers to external factors in the surface of the body, such as caused by trauma,
hematoma, wound, foreign body, infection after surgery, the surface